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Heart Health™ Advanced Co-Q10 (Cardiovascular & Immune Support)
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- CoQ10 concentrations naturally diminish with age and deficiency has been associated with certain health concerns; the body’s ability to synthesize normal amounts of CoQ10 is inhibited by one class of cholesterol-lowering drugs
- CoQ10 is a fat-soluble coenzyme, which is a substance that is necessary to, or supports the action of an enzyme
- CoQ10 is a potent antioxidant that is known to scavenge oxygen radicals in the mitochondria during oxidative phosphorylation
- CoQ10 is essential for the production of energy in every cell of the human body
- CoQ10 is a component of the electron-transport that is required to manufacture adenosine triphosphate (ATP)
- CoQ10 is known as ubiquinone, a substance that is similar in structure to a vitamin and is found mainly in mitochondria throughout the body
- CoQ10 resides in the membranes of the cells’ mitochondria
- Enhances traditional support of cardiovascular health
- Helps maintain healthy blood sugar levels
- Helps maintain heart muscle strength
- Helps maintain normal blood pressure
- Promotes/boosts the immune system
- Promotes cardiovascular health
- Promotes gum health
- Promotes head comfort
- Helps maintain healthy cholesterol levels
- Provides antioxidant protection for the cardiovascular system
- Studies have found CoQ10 deficiencies in overweight people
- Supports/Helps maintain brain health
- Vital for ATP production and supports muscle endurance
Gluten-Free - The finished product contains no detectable gluten (<10ppm gluten)
No Detectable GMOs - The finished product contains no detectable genetically-modified organisms
Quality Standards - GMP Operations and Standardized Ingredients
Checked For: Heavy Metals, Microbiological Contaminants, Allergens, Residual Solvents, Potency, Purity and Identity
Why Choose Heart Health Co-Q10?
Heart disease is the leading cause of death in the United States and worldwide for both men and women. Many factors may contribute to poor heart health, such as regularly eating an unhealthy diet of processed, high-calorie and high-fat foods, smoking, or living a sedentary lifestyle. Equally, uncontrollable elements, like pollution, may also put you at risk for cardiovascular issues.
Clinical studies have shown that supplementing with Coenzyme Q10 (CoQ10) may be beneficial in promoting cardiovascular health. CoQ10 is a coenzyme, meaning that it is essential to activating enzymes. Enzymes are produced by the body and are necessary for survival and healthy living. CoQ10 is known as a ubiquinone and is found in every cell in the body. It is important for cellular energy production, promoting the strength of the heart muscle and providing antioxidant protection to the cardiovascular system.*
Heart Health™ Advanced Co-Q10 is a blend of CoQSol-CF®† and vitamin E, designed to promote overall cardiovascular health. It helps maintain normal blood pressure, healthy cholesterol levels and heart muscle strength. It also provides antioxidant protection for the cardiovascular system and promotes cellular energy production.*
Coenzyme Q10 (CoQSol-CF®)†: 100 mg
Coenzyme Q10 belongs to a family of substances called ubiquinones and is a water-insoluble, wax-like substance that is part of the respiratory chain. Since it is a coenzyme, it is necessary to support the action of an enzyme. CoQ10 is found in each of the trillions of cells throughout the body, except for mature red blood cells. It has a multitude of health benefits at the cellular level, in the cardiovascular system and with the body’s metabolism.
Much is known about the biochemistry of CoQ10. CoQ10 is a two-part compound that is composed of a long, fat-soluble isoprenoid tail that anchors the molecule in the inner membrane of the mitochondria, and quinine that is capable of accepting and transferring electrons through a portion of the respiratory chain. The “Q” stands for quinine and the “10” stands for the number of isoprenoid units in the tail portion of the molecule. It is synthesized in the cells, and is involved in electron transport and energy production in mitochondria.
All cellular functions depend upon the production of adenosine triphosphate (ATP). ATP is a molecule with three high-energy phosphate bonds, and is the primary energy source for many metabolic processes. CoQ10 is essential to the ATP production process. The heart has a high metabolic demand, which is why normal levels of CoQ10 are associated with good cardiovascular health. As part of the energy production process, CoQ10 functions to generate energy from oxygen, in the form of ATP, for bodily processes. CoQ10 serves as a free radical scavenger and an antioxidant. The antioxidant activity in the mitochondria and cell membranes protects against peroxidation of lipid membranes. Combining CoQ10 with vitamin E generates a synergistic antioxidant effect on lipoprotein and spares the vitamin E.
CoQSol-CF® is a unique, patent-pending formula including these ingredients: CoQ10, food grade d-limonene (which serves as a non-polar, organic solvent), and tocopherols ( a form of vitamin E). This combination of ingredients creates a liquid, crystal-free solution of CoQ10 that provides enhanced bioavailability.
† CoQSol-CF® is a registered trademark of Soft Gel Technologies.
Vitamin E (d-alpha-Tocopherol): 134 mg
Vitamin E is a family of related compounds called tocopherols and tocotrienols. It is available in a natural or synthetic form. In most cases, the natural and synthetic forms are identical except the natural form of vitamin E is better absorbed and retained in the body. Along with vitamins A, D and K, vitamin E is a fat-soluble vitamin. For those individuals watching their dietary fat consumption, vitamin E intake is likely to be low due to a reduced intake of foods with high fat content.*
Vitamin E is one of the most powerful fat-soluble antioxidants in the body. It helps protect cell membranes from the effects of free radicals.* Additionally, high intakes of vitamin E has been found to support cardiovascular health.*
What type of vitamin E is in Advanced Coenzyme Q10?
The natural form of vitamin E, d-Alpha-Tocopherol, is in Advance Coenzyme Q10. It is far superior to synthetic in terms of retention in the body and absorption.
If my body makes CoQ10, why should I take a supplement?
When you are young, your body can produce adequate levels of CoQ10. However, as you get older, your cells do not produce enough of the energy they need to function well. The body‘s ability to synthesize CoQ10 begins to decline. Supplementation of CoQ10 has been shown to raise blood levels of the coenzyme when the body’s ability to synthesize it begins to decrease.
What is the recommended serving size of CoQ10?
CoQ10 has been used in maintenance servings of 30-60 mg, but can go up to 100 mg or more.
Is there a certain time I should take CoQ10?
CoQ10 should be taken with a meal containing some fat. However, taking it in combination with soy or vegetable oil substantially enhances it absorption.
Is it okay to take a CoQ10 supplement while pregnant or nursing?
No. The safety of CoQ10 has not been established in pregnancy and lactation.
Is it safe to take CoQ10?
Yes. It does not produce any toxic side effects when ingested by humans or animals. It is listed in the 42nd edition of the Physicians’ Desk Reference as replacement therapy for a nutrient, and no adverse reactions are listed.
- Kagan, V, et al. Coenzyme Q: Its role in scavenging and generation of radicals in membranes. In Handbook of Antioxidants, eds. Enrique Cadenas and Lester Packer, New York, Marcel Dekker, Inc., 1996, pp. 157-201.
- Littarru, G.P. et al. Clinical aspects of coenzyme Q: Improvement of cellular bioenergetics or antioxidant protection? In Handbook of Antioxidants, eds. E. Cadenas and L. Packer: New York, Marcel Dekker, Inc., 1996, pp. 203-239.
- Greenberg, S. and Frishman, W.H. Coenzyme Q10: A new drug for cardiovascular disease. Journal of Clinical Pharmacology 30: 596-608, 1990.
- Chello, M, et al. Protection of coenzyme Q10 from myocardial reperfusion injury during coronary artery bypass grafting. Annals of Thoracic Surgery 58: 1427-1432, 1994.
- Lansjoen, P.H. et al. Response of patients in classes III and IV of cardiomyopathy to therapy in a blind crossover trial with coenzyme Q10. Proceedings of the National Academy of Sciences USA 82: 4240, 1985.
- Stryer, L. Biochemistry, 2nd ed. New York, W.H. Freeman and Company, 1981.
- Firstein, R. The Nutraceutical Revolution. New York , Riverhead Books, 1998.
- Frei, B, et al. Ubiquinol-10 is an effective lipid-soluble antioxidant at physiological concentrations. Proceedings of the National Academy of Sciences USA 87: 4879-4883, 1990.
- Hanaki, Y. et al. Ratio of low-density lipoprotein cholesterol to ubiquinone as a coronary risk factor: New England Journal of Medicine, 325: 814-815, 1991.
- Singh R.B. and Singh M.M. Effects of coenzyme Q10 in new indications with antioxidant vitamin deficiency. Journal of Nutritional and Environmental Medicine 9: 223-228, 1999.
- Greenburg S. and Frishman W. Coenzyme Q10: A new drug from myocardial ischemia? Medical Clinics of North America 72: 243-58, 1998.
- Langsjoen, P.H. et al. Pronounced increase of survival of patients with cardiomyopathy when treated with coenzyme Q10 and conventional therapy. International Journal of Tissue Reactions 12: 163-168, 1990.
- Digiesi, V. et al. Mechanism of action of coenzyme Q10 in essential hypertension. Current Therapy and Research 51: 668-672, 1992.
- Sunamori, M. et al. Clinical experience of coenzyme Q10 to enhance intraoperative myocardial protection in coronary artery revascularization. Cardiovascular Drugs and Therapy 5: 297-300, 1991.
- Langsjoen, P.H. et al. A six-year clinical study of therapy of cardiomyopathy with coenzyme Q10. International Journal of Tissue Reactions 12: 169-71, 199.
- Stocker, R. et al. Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation than does alpha-tocopherol. Proceedings of the National Academy of Sciences USA 88: 1646-1650, 1991.
- Shi, H. and Noguchi, N. Dynamics of antioxidant action of ubiquinol: A reappraisal. Biofactors 9: 141-148, 1999.
- Folkers, K. et al. Effect of coenzyme Q10 on serum levels of creatine phosphokinase in preclinical muscular dystrophy. Proceedings of the National Academy of Sciences USA 71: 2098, 1974.
- Folkers, K. et al. Biochemical rationale and the cardiac response of patients with muscle disease to therapy with coenzyme Q10. Proceedings of the National Academy of Sciences USA 82: 4513, 1985.
- Chen Y.F., Lin Y.T. and Wu S.C. Effectiveness of coenzyme Q10 on myocardial preservation during hypothermic cardioplegic arrest. Journal of Thoracic and Cardiovascular Surgery 107: 242-247, 1994.
- Murray, M.T. Encyclopedia of Natural Medicine, Rocklin , CA , Prima Publishing, 1998.
- Folkers, K et al. The activities of coenzyme and vitamin B6 for immune responses. Biochemical and Biophysical Research Communications 193: 88-92, 1993.
- Folkers, K et al. Coenzyme Q10 increases T4/T8 ratios of lymphocytes in ordinary subjects and relevance to patients having the AIDS-related complex. Biochemical and Biophysical Research Communications 176: 25.
- Lockwood, K. et al. Partial and complete regression of breast cancer in patients in relation to dosage of Coenzyme Q10. Biomedical and Biophysical Research Communications 199: 1504-1508, 1994.
- Nakamura, R. et al. Study of Co Q10-enzymes in gingival tissues from patients with periodontal disease and evidence for a deficiency of coenzyme Q10. Proceedings of the National Academy of Sciences USA 71: 1456, 1974.
- Littarru, G.P. et al. Deficiency of coenzyme Q10 in gingival tissue from patients with periodontal disease. Proceedings of National Academy of Sciences USA 68: 2332, 1971.
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Love this product as well as many others in the nutrMetrix Line. The quality and the synergy of the ingredients , with special attention to avoiding crysallization makes this the best choice to help keep your cellular health at optimal levels .
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Amazing heart health product
Love this product. It has made a great difference in our health.
Response from Customer Service
Dear Valued Customer,
Thank you for taking the time to leave your thoughts on the Heart Health™ Advanced Co-Q10! We are happy to hear you are pleased with the product.
Thank you again!
The Product Information Team
I use many products from this company and this is just one more I feel happy I consume. The quality is the BEST!
Keep your heart healthy
I take this along with isotonix daily essentials. At 61 I couldn't feel any better. All my blood test are normal. I need No medications. I even work a very physical job as a delivery person for FedEx. I tell others about the importance of using supplements to keep up their health, especially Co Q 10.
I love this product
As a person who is aging and in her 7th decade, I know CoQ10 is diminished. Mitochondria are really important and this product supports the the mitochondria from oxidation by scavenging free radicals