Breaking the stress weight-gain cycle.

• May help to minimize certain stress-related issues (weight gain, difficulty sleeping, etc.)
• Helps to reduce stress placed on the adrenals to perform, thereby helping to decrease the possibility of adrenal fatigue
• May help to support normal hypothalamic-pituitary-adrenal (HPA) functions
• May help support stress-related adrenal functions
• Helps to promote healthy levels of cortisol
• Helps maintain healthy levels of both serotonin and dopamine
• Helps support mood
• Helps to support emotional responses to stress
• May help to maintain normal thyroid function

Your job demands a lot of your time, and your family demands just as much, if not more. Trips to the mailbox are greeted by bills. Every day, life is taking its toll on you. Even in seemingly good times, stress is something we cannot escape. And it not only has a harmful effect on us mentally, but it can also wreak havoc on us physically — including on our waistlines.*

When we are faced with stress, our bodies go into a “fight or flight” response, and the adrenal gland releases hormones that give the body a burst of energy and strength. This response used to be beneficial to our ancestors, allowing their bodies to physically fight or run away when faced with danger. But today, this response acts much differently, taking place because of stressful days at the office or a traffic jam on your way home. The body’s response is supposed to return to normal once the perceived threat is gone, but if increased stress levels keep that from happening, it could have a negative effect. In fact, the resulting symptoms could include adrenal fatigue, suppressed thyroid function, an imbalance in blood sugar levels and increased abdominal (adipose) fat.*

One of the hormones released during this “fight or flight” response is cortisol, which increases blood sugar, suppresses the immune system and aids in fat, protein and carbohydrate metabolism. Under normal circumstances, cortisol helps restore homeostasis after stress. The problem is that constant stress leads to a constant state of cortisol production, which stimulates glucose production. This excess glucose is typically converted into fat, ending up as stored fat. High cortisol levels can also lead to binge eating. High cortisol levels not only make you want to keep snacking but also contribute to storing more belly fat, which is a bit harder to lose.*

Cortisol levels also have a direct relationship with the thyroid. They act synergistically with one another. Cortisol assists the thyroid hormone in working more efficiently, and the correct amount of cortisol — not too high or too low — supports normal thyroid function. When cortisol gets too high, triggered by the adrenal gland’s response to elevated stress, it causes a delayed response to the thyroid hormone receptors. When this occurs, the hormones aren't allowed to work at optimal levels, leaving you feeling sluggish. And that leads to a higher chance of stress eating and giving up physical activity.*

When you're battling adrenal fatigue, it is difficult to lose weight for several reasons. You are exhausted and lack the physical energy to exercise the way you used to. Adrenal fatigue can also cause cravings for high-fat sweets and salty foods, turning food into a form of comfort and aid in assisting the body’s exhausted adrenal glands. This combination of being sedentary, having no energy and eating chips and cookies makes it seemingly impossible to lose weight. But there is hope, and it can be done without worsening your already delicate state of health — and without feeling famished.*

GoTrim ACTS Adrenal, Cortisol, Thyroid & Stress Support Formula, specially formulated with holy basil and ashwagandha, works specifically to promote healthy adrenal gland function, cortisol levels and thyroid function. It helps control stress levels and minimize weight gain associated with increased stress. Unlike the competitors, GoTrim ACTS doesn't mask the problem of weight gain — it addresses the root of the problem by helping your body adapt to stress and assisting you with your weight management goals.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

±Individuals following the GoTrim^® Lifestyle System as part of a healthy diet and exercise program can expect to lose 1-2 pounds per week.

^‡As Sensoril^®. Sensoril is a registered trademark of Natreon, Inc. and is protected under U.S. Patent #7,318,938.

^†As Bacopin^®. Bacopin is a registered trademark of Sabinsa Corporation.

Sensoril^®‡ Trim/Ashwagandha Root Extract
Ashwagandha has antioxidant properties. It has been proven to act as an adaptogen by helping to inhibit occasional fatigue, boost energy, promote emotional well-being and help counteract the negative effects of stress. Preliminary evidence suggests ashwagandha helps to regulate stress-induced levels of dopamine receptors in the corpus striatum of the brain. It also appears to promote normal levels of plasma corticosterone, blood urea nitrogen and blood lactic acid. Acting as an adaptogen, ashwagandha reduces stress placed on the adrenals to perform, thereby helping to decrease the possibility of adrenal fatigue. Though the exact mechanisms by which ashwagandha works are unknown, one hypothesis is that it functions by way of GABA-mimetic activity, which acts independently of GABA (gamma-aminobutyric acid) receptors. In addition to its adaptogenic properties, ashwagandha may promote normal regulation of thyroid function. It has been shown to promote healthy serum levels of the thyroid hormones triiodothyronine (T₃) and thyroxine (T₄), which are important in promoting normal metabolism.

Holy Basil
Holy basil has adaptogenic and calming activities. Research shows holy basil may help to promote normal plasma corticosterone levels, hepatic function and renal function, maintain normal blood glucose levels and help inhibit several other stress-related issues. Though the exact mechanism of action is not known, it is believed that much of holy basil's effect comes from its high content of eugenol, caryophyllene and triterpenoids, such as ursolic and oleanolic acids.

L-Theanine
L-theanine is an amino acid found in green tea and some mushrooms. Preliminary evidence suggests that l-theanine might induce subjective feelings of tranquility in healthy people. It is believed that l-theanine may work by promoting normal levels of the neurotransmitters GABA and dopamine in the central nervous system. GABA is the primary inhibitory neurotransmitter that promotes calming effects at the cellular level. Dopamine aids in regulating many functions within the brain regarding behavior, cognition, sleep, mood, attention and memory, and it’s often associated with the brain's ‘reward’ or ‘pleasure’ center.

Passionflower Extract
Passionflower has relaxation effects. Some studies have pointed to the flavonoids in passionflower, such as apigenin, vitexin and isovitexin, as the primary constituents responsible for its effects. Research suggests apigenin can bind to central benzodiazepine receptors in the brain, possibly causing relaxation and helping regulate mood without impairing memory or motor skills.

Bacopin^®† (Bacopa monniera Leaf)
Bacopa monniera, also referred to as Brahmi, has a long history of use in Ayurvedic health to support memory, learning and mood. Constituents of bacopa, specifically bacosides A and B, have been shown to support learning ability, cognitive performance and mood. Bacopa also contains the flavonoids apigenin and luteolin. Research suggests apigenin can bind to central benzodiazepine receptors in the brain, possibly causing relaxation and helping regulate mood without impairing memory or motor skills.

Rhodiola Rosea Root Extract
Rhodiola, or roseroot, acts as an antioxidant and adaptogen, promoting relaxation and mental clarity. It also helps to support mood. Research suggests that salidroside, one of over 30 compounds found in Rhodiola, is responsible for its stimulating and adaptogenic effects. Within the brain, Rhodiola appears to influence the level, activity and transport of monoamine neurotransmitters, such as dopamine, epinephrine, norepinephrine and serotonin. Rhodiola has been proposed to promote healthy neurotransmitter levels.

Iodine
The Atlantic kelp-derived iodine in this formula has the most important function of promoting normal thyroid function and contributing to the body’s normal production of thyroid hormones. Iodine is crucial in maintaining thyroid health.

Eleuthero Root (Eleutherococcus senticosus) Extract
Research has shown that eleuthero root, also known as “Siberian ginseng,” has antioxidant and adaptogenic effects as well as many others. As an adaptogen, it helps promote normal regulation of the endocrine system's response to stressors. The active compounds in eleuthero root, eleutherosides, are believed to stimulate the pituitary-adrenocortical system, allowing for more efficient regulation of the stress response and healthy cortisol levels. Other research suggests that it may help to support feelings of well-being, reduce occasional fatigue and support memory and cognitive performance.